Endocrine Abstracts

Introduction: Adolescent and young adult differentiated thyroid cancers are frequently under diagnosed forms. They would be characterized by their aggressiveness and the presence of particular histological forms. The aim of the study was to describe the characteristics of thyroid carcinoma in adolescents and young adults by analyzing the clinical, histological, therapeutic and evolutionary characteristics.Materials and methods: We conducted a retrospecti...

Introduction: Hematologic abnormalities are frequently observed during hyperthyroidism and are related to complex multifactorial pathogenic mechanisms that are still poorly understood and may affect the three hematopoietic lineages in isolation or in combination. These abnormalities are exceptionally revealing and are usually subclinical. For the endocrinologist, they raise the problem of the risk of their aggravation under the hematotoxic effect of synthetic antithyroid drugs...

Introduction: Epidemiological studies have reported that being overweight and being obese are associated with increased incidences of numerous cancers, including thyroid cancer. In addition to cancer risk, obesity has also been demonstrated to be associated with more aggressive pathological characteristics of the tumor and worse prognosis in patients with several cancers.Purpose of study: Demonstrate the relationships between BMI and the clinico-patholog...

Introduction: The association of thyroid and colon cancer is rare, it can be observed in the context of Gardner’s syndrome and Cowden’s syndrome with a prevalence of 0.6%. We report a case of metachronous association of a differentiated thyroid cancer with a colon cancer.Observation: 45-year-old patient, followed for well-differentiated colonic adenocarcinoma without metastasis, having received eight courses of chemotherapy. One year later, the...

Background: Several studies have demonstrated the relationship between breast cancer and thyroid cancer by the presence of common genetic determinants. The aim of the study was to define the breast cancer prevalence among patients followed for thyroid carcinoma and to determine factors favoring this association.Matherials and methods: A Cross-sectional study was conducted in the Ibn Rochd University Hospital Endocrinology and Diabetology department of Ca...

Introduction: Although the most common cause of thyrotoxicosis is Graves’ disease, identification of other causes is important to establish appropriate management. The diagnosis of factitious thyrotoxicosis often presents a difficult challengebut should not be overlooked. We report a case of a patient with treated thyroid carcinoma who presented with factitious hyperthyroidism.Observation: 50-year-old patient, followed for papillary thyroid microcar...

Introduction: Medullary thyroid carcinoma (MTC) is a rare and silent endocrine tumor representing 5-10% of thyroid cancers. It is the most aggressive form of thyroid carcinoma, usually diagnosed at advanced stages.Purpose of study: Study the phenotypic and genotypic profiles as well as the anatomical-histological characteristics related to the recurrence of the disease.Matherials and methods: Descriptive cross-sectional study inclu...

IntroductionPrimary thyroid lymphomas (LTP) are a rare entity, characterized by their histological and clinical heterogeneity. They represent 5% of thyroid tumors and 2% of extra-ganglionic lymphomas. We report two observations of LTP by specifying the epidemiological, diagnostic and therapeutic features.ObservationsObservation 170-year-old patient, followed in internal medicine for Sd ...

IntroductionBasedow disease is the most common etiology of hyperthyroidism; the cardiac manifestations seen in hyperthyroidism often affect people over 60 years of age, manifested mainly by sinus tachycardia, atrial rhythm disturbances or increased cardiac output. Pulmonary arterial hypertension and pulmonary embolism are atypical manifestations.Observation39-year-old patient, followed for basedow disease for...

IntroductionPapillary carcinoma is the most frequent histological form of malignant thyroid tumors, increasingly diagnosed at the microcarcinoma stage. Papillary microcarcinomas, often localized, are classified as very low risk.Objective of the studyTo describe the epidemiological and clinical characteristics, the evolutionary profile as well as to determine the predictive factors of recurrence of papillary m...